A man and woman died Tuesday morning when their vehicle was hit on U.S. 17 at Village Square Parkway.
The Florida Highway Patrol says a pickup truck traveling south on US 17 ran the red light, t-boning the other vehicle on the driver's side.
Both the driver and passenger in the second vehicle were killed and the FHP says the driver who ran the red light stayed on the scene and is cooperating with investigators.
For a few hours southbound traffic on U.S. 17 was re-routed off County Road 220, but all lanes of US17 in both directions are now open.
Troopers couldn't offer too many details on the people who died, other than saying they were not children.
It's not clear what led the pickup truck driver to run the red light.